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From Automation to Autonomy: A Survey on Large Language Models in Scientific Discovery
PhD Qualifying Examination Title: "From Automation to Autonomy: A Survey on Large Language Models in Scientific Discovery" by Mr. Tianshi ZHENG Abstract: Large Language Models (LLMs) are catalyzing a paradigm shift in scientific discovery, evolving from task-specific automation tools into increasingly autonomous agents and fundamentally redefining research processes and human-AI collaboration. This survey systematically charts this burgeoning field, placing a central focus on the changing roles and escalating capabilities of LLMs in science. Through the lens of the scientific method, we introduce a foundational three-level taxonomy—Tool, Analyst, and Scientist—to delineate their escalating autonomy and evolving responsibilities within the research lifecycle. We further identify pivotal challenges and future research trajectories such as robotic automation, self-improvement, and ethical governance. Overall, this survey provides a conceptual architecture and strategic foresight to navigate and shape the future of AI-driven scientific discovery, fostering both rapid innovation and responsible advancement. Date: Tuesday, 14 October 2025 Time: 4:00pm - 6:00pm Venue: Room 5501 Lifts 25/26 Committee Members: Dr. Yangqiu Song (Supervisor) Dr .Junxian He (Chairperson) Dr. May Fung