UNIQUIMER3D, a software system for structural DNA nanotechnology design, analysis and evaluation

MPhil Thesis Defence


Title: "UNIQUIMER3D, a software system for structural DNA nanotechnology design,
analysis and evaluation"

By

Mr. Jinhao Zhu


Abstract

In this thesis, A user-friendly software system, UNIQUIMER 3D, was
developed. This system has functions for 3D visualization, energy
minimization, sequence generation, and construction of motif array
simulations (2D tiles & 3D lattices). The system can check the structural
deformation and design errors under scaled-up conditions. The system aims
to facilitate the design of novel DNA motifs for the DNA nanotechnology.
The program has been tested for the design of existing motifs (holiday
junction, 4x4 tile, DX, DNA tetrahedron, DNA cube, etc.) The software is
provided free of charge to the non-profit research institutions. The
software was developed for the Windows environment.


Date:				Monday, 25 August 2008

Time:				10:00a.m.-12:00noon

Venue:				Room 3501
				Lifts 25-26

Committee Members:		Dr. Chi-Keung Tang (Supervisor)
				Prof. Yongli Mi (Supervisor, CBME)
				Prof. Dit-Yan Yeung (Chairperson)
				Dr. Henry Lam (CBME)


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